Fentanyl sublingual spray fsls is a sublingually administered formulation of fentanyl available in doses of 100 200 400 600 and 800 ug strengths approved in the usa for the management of breakthrough pain in adult cancer patients already receiving and who are tolerant to opioid therapy for their underlying persistent cancer pain. 175 background sublingual fentanyl spray is indicated for the treatment of breakthrough cancer pain btcp in opioid tolerant patients receiving around the clock atc opioids this post hoc analysis characterized patients receiving atc transdermal fentanyl patch tfp who also received fentanyl sublingual spray for btcp during a phase 3 randomized placebo controlled trial. The sublingual fentanyl tablet is indicated for the management of breakthrough pain in patients with cancer who are already receiving opioid therapy for their background cancer pain the pharmacokinetic efficacy tolerability and safety profile of the sublingual fentanyl tablet suggests that it has a valuable role to play in the symptomatic . A 74 year old man uses long acting opioids for chest wall pain associated with lung cancer he experiences breakthrough pain in the evenings and would like advice about the best way to treat it . And drug administration fda approved for the management of breakthrough cancer pain in patients who are already receiving and who are tolerant to around the clock therapy for their underlying persistent cancer pain five different dosage forms of immediate release fentanyl are currently available a sublingual tablet abstral a transmucosal
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